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  1. Preface
  2. 1 An Invisible World
    1. Introduction
    2. 1.1 What Our Ancestors Knew
    3. 1.2 A Systematic Approach
    4. 1.3 Types of Microorganisms
    5. Summary
    6. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  3. 2 How We See the Invisible World
    1. Introduction
    2. 2.1 The Properties of Light
    3. 2.2 Peering Into the Invisible World
    4. 2.3 Instruments of Microscopy
    5. 2.4 Staining Microscopic Specimens
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  4. 3 The Cell
    1. Introduction
    2. 3.1 Spontaneous Generation
    3. 3.2 Foundations of Modern Cell Theory
    4. 3.3 Unique Characteristics of Prokaryotic Cells
    5. 3.4 Unique Characteristics of Eukaryotic Cells
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  5. 4 Prokaryotic Diversity
    1. Introduction
    2. 4.1 Prokaryote Habitats, Relationships, and Microbiomes
    3. 4.2 Proteobacteria
    4. 4.3 Nonproteobacteria Gram-Negative Bacteria and Phototrophic Bacteria
    5. 4.4 Gram-Positive Bacteria
    6. 4.5 Deeply Branching Bacteria
    7. 4.6 Archaea
    8. Summary
    9. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  6. 5 The Eukaryotes of Microbiology
    1. Introduction
    2. 5.1 Unicellular Eukaryotic Parasites
    3. 5.2 Parasitic Helminths
    4. 5.3 Fungi
    5. 5.4 Algae
    6. 5.5 Lichens
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  7. 6 Acellular Pathogens
    1. Introduction
    2. 6.1 Viruses
    3. 6.2 The Viral Life Cycle
    4. 6.3 Isolation, Culture, and Identification of Viruses
    5. 6.4 Viroids, Virusoids, and Prions
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  8. 7 Microbial Biochemistry
    1. Introduction
    2. 7.1 Organic Molecules
    3. 7.2 Carbohydrates
    4. 7.3 Lipids
    5. 7.4 Proteins
    6. 7.5 Using Biochemistry to Identify Microorganisms
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. True/False
      3. Matching
      4. Fill in the Blank
      5. Short Answer
      6. Critical Thinking
  9. 8 Microbial Metabolism
    1. Introduction
    2. 8.1 Energy, Matter, and Enzymes
    3. 8.2 Catabolism of Carbohydrates
    4. 8.3 Cellular Respiration
    5. 8.4 Fermentation
    6. 8.5 Catabolism of Lipids and Proteins
    7. 8.6 Photosynthesis
    8. 8.7 Biogeochemical Cycles
    9. Summary
    10. Review Questions
      1. Multiple Choice
      2. True/False
      3. Matching
      4. Fill in the Blank
      5. Short Answer
      6. Critical Thinking
  10. 9 Microbial Growth
    1. Introduction
    2. 9.1 How Microbes Grow
    3. 9.2 Oxygen Requirements for Microbial Growth
    4. 9.3 The Effects of pH on Microbial Growth
    5. 9.4 Temperature and Microbial Growth
    6. 9.5 Other Environmental Conditions that Affect Growth
    7. 9.6 Media Used for Bacterial Growth
    8. Summary
    9. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  11. 10 Biochemistry of the Genome
    1. Introduction
    2. 10.1 Using Microbiology to Discover the Secrets of Life
    3. 10.2 Structure and Function of DNA
    4. 10.3 Structure and Function of RNA
    5. 10.4 Structure and Function of Cellular Genomes
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. True/False
      3. Matching
      4. Fill in the Blank
      5. Short Answer
      6. Critical Thinking
  12. 11 Mechanisms of Microbial Genetics
    1. Introduction
    2. 11.1 The Functions of Genetic Material
    3. 11.2 DNA Replication
    4. 11.3 RNA Transcription
    5. 11.4 Protein Synthesis (Translation)
    6. 11.5 Mutations
    7. 11.6 How Asexual Prokaryotes Achieve Genetic Diversity
    8. 11.7 Gene Regulation: Operon Theory
    9. Summary
    10. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  13. 12 Modern Applications of Microbial Genetics
    1. Introduction
    2. 12.1 Microbes and the Tools of Genetic Engineering
    3. 12.2 Visualizing and Characterizing DNA, RNA, and Protein
    4. 12.3 Whole Genome Methods and Pharmaceutical Applications of Genetic Engineering
    5. 12.4 Gene Therapy
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  14. 13 Control of Microbial Growth
    1. Introduction
    2. 13.1 Controlling Microbial Growth
    3. 13.2 Using Physical Methods to Control Microorganisms
    4. 13.3 Using Chemicals to Control Microorganisms
    5. 13.4 Testing the Effectiveness of Antiseptics and Disinfectants
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  15. 14 Antimicrobial Drugs
    1. Introduction
    2. 14.1 History of Chemotherapy and Antimicrobial Discovery
    3. 14.2 Fundamentals of Antimicrobial Chemotherapy
    4. 14.3 Mechanisms of Antibacterial Drugs
    5. 14.4 Mechanisms of Other Antimicrobial Drugs
    6. 14.5 Drug Resistance
    7. 14.6 Testing the Effectiveness of Antimicrobials
    8. 14.7 Current Strategies for Antimicrobial Discovery
    9. Summary
    10. Review Questions
      1. Multiple Choice
      2. True/False
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  16. 15 Microbial Mechanisms of Pathogenicity
    1. Introduction
    2. 15.1 Characteristics of Infectious Disease
    3. 15.2 How Pathogens Cause Disease
    4. 15.3 Virulence Factors of Bacterial and Viral Pathogens
    5. 15.4 Virulence Factors of Eukaryotic Pathogens
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  17. 16 Disease and Epidemiology
    1. Introduction
    2. 16.1 The Language of Epidemiologists
    3. 16.2 Tracking Infectious Diseases
    4. 16.3 Modes of Disease Transmission
    5. 16.4 Global Public Health
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  18. 17 Innate Nonspecific Host Defenses
    1. Introduction
    2. 17.1 Physical Defenses
    3. 17.2 Chemical Defenses
    4. 17.3 Cellular Defenses
    5. 17.4 Pathogen Recognition and Phagocytosis
    6. 17.5 Inflammation and Fever
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  19. 18 Adaptive Specific Host Defenses
    1. Introduction
    2. 18.1 Overview of Specific Adaptive Immunity
    3. 18.2 Major Histocompatibility Complexes and Antigen-Presenting Cells
    4. 18.3 T Lymphocytes and Cellular Immunity
    5. 18.4 B Lymphocytes and Humoral Immunity
    6. 18.5 Vaccines
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  20. 19 Diseases of the Immune System
    1. Introduction
    2. 19.1 Hypersensitivities
    3. 19.2 Autoimmune Disorders
    4. 19.3 Organ Transplantation and Rejection
    5. 19.4 Immunodeficiency
    6. 19.5 Cancer Immunobiology and Immunotherapy
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  21. 20 Laboratory Analysis of the Immune Response
    1. Introduction
    2. 20.1 Polyclonal and Monoclonal Antibody Production
    3. 20.2 Detecting Antigen-Antibody Complexes
    4. 20.3 Agglutination Assays
    5. 20.4 EIAs and ELISAs
    6. 20.5 Fluorescent Antibody Techniques
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  22. 21 Skin and Eye Infections
    1. Introduction
    2. 21.1 Anatomy and Normal Microbiota of the Skin and Eyes
    3. 21.2 Bacterial Infections of the Skin and Eyes
    4. 21.3 Viral Infections of the Skin and Eyes
    5. 21.4 Mycoses of the Skin
    6. 21.5 Protozoan and Helminthic Infections of the Skin and Eyes
    7. Summary
    8. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  23. 22 Respiratory System Infections
    1. Introduction
    2. 22.1 Anatomy and Normal Microbiota of the Respiratory Tract
    3. 22.2 Bacterial Infections of the Respiratory Tract
    4. 22.3 Viral Infections of the Respiratory Tract
    5. 22.4 Respiratory Mycoses
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  24. 23 Urogenital System Infections
    1. Introduction
    2. 23.1 Anatomy and Normal Microbiota of the Urogenital Tract
    3. 23.2 Bacterial Infections of the Urinary System
    4. 23.3 Bacterial Infections of the Reproductive System
    5. 23.4 Viral Infections of the Reproductive System
    6. 23.5 Fungal Infections of the Reproductive System
    7. 23.6 Protozoan Infections of the Urogenital System
    8. Summary
    9. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  25. 24 Digestive System Infections
    1. Introduction
    2. 24.1 Anatomy and Normal Microbiota of the Digestive System
    3. 24.2 Microbial Diseases of the Mouth and Oral Cavity
    4. 24.3 Bacterial Infections of the Gastrointestinal Tract
    5. 24.4 Viral Infections of the Gastrointestinal Tract
    6. 24.5 Protozoan Infections of the Gastrointestinal Tract
    7. 24.6 Helminthic Infections of the Gastrointestinal Tract
    8. Summary
    9. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  26. 25 Circulatory and Lymphatic System Infections
    1. Introduction
    2. 25.1 Anatomy of the Circulatory and Lymphatic Systems
    3. 25.2 Bacterial Infections of the Circulatory and Lymphatic Systems
    4. 25.3 Viral Infections of the Circulatory and Lymphatic Systems
    5. 25.4 Parasitic Infections of the Circulatory and Lymphatic Systems
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Fill in the Blank
      3. Short Answer
      4. Critical Thinking
  27. 26 Nervous System Infections
    1. Introduction
    2. 26.1 Anatomy of the Nervous System
    3. 26.2 Bacterial Diseases of the Nervous System
    4. 26.3 Acellular Diseases of the Nervous System
    5. 26.4 Fungal and Parasitic Diseases of the Nervous System
    6. Summary
    7. Review Questions
      1. Multiple Choice
      2. Matching
      3. Fill in the Blank
      4. Short Answer
      5. Critical Thinking
  28. A | Fundamentals of Physics and Chemistry Important to Microbiology
  29. B | Mathematical Basics
  30. C | Metabolic Pathways
  31. D | Taxonomy of Clinically Relevant Microorganisms
  32. E | Glossary
  33. Answer Key
    1. Chapter 1
    2. Chapter 2
    3. Chapter 3
    4. Chapter 4
    5. Chapter 5
    6. Chapter 6
    7. Chapter 7
    8. Chapter 8
    9. Chapter 9
    10. Chapter 10
    11. Chapter 11
    12. Chapter 12
    13. Chapter 13
    14. Chapter 14
    15. Chapter 15
    16. Chapter 16
    17. Chapter 17
    18. Chapter 18
    19. Chapter 19
    20. Chapter 20
    21. Chapter 21
    22. Chapter 22
    23. Chapter 23
    24. Chapter 24
    25. Chapter 25
    26. Chapter 26
  34. Index
Symbols
3-phosphoglycerate8.6 Photosynthesis
α carbon7.4 Proteins
α-helix7.4 Proteins
β-pleated sheet7.4 Proteins
A
ABO blood group system19.1 Hypersensitivities
acetone-butanol-ethanol fermentation8.4 Fermentation
Acetothermus paucivorans4.5 Deeply Branching Bacteria
acquired immunodeficiency syndrome (AIDS)19.4 Immunodeficiency
acridine orange11.5 Mutations
activated macrophages19.1 Hypersensitivities
activation of cytotoxic T cells18.3 T Lymphocytes and Cellular Immunity
Active immunity18.5 Vaccines
acute inflammation17.5 Inflammation and Fever
acute necrotizing ulcerative gingivitis24.2 Microbial Diseases of the Mouth and Oral Cavity
adenosine deaminase deficiency12.4 Gene Therapy
adenosine diphosphate (ADP)8.1 Energy, Matter, and Enzymes
adenosine monophosphate (AMP)8.1 Energy, Matter, and Enzymes
adipose tissue7.3 Lipids
aerial filaments9.1 How Microbes Grow
affitins4.6 Archaea
Agrobacterium4.2 Proteobacteria
Alcanivorax borkumensis8.7 Biogeochemical Cycles
alcohol fermentation8.4 Fermentation
Alexandrium5.4 Algae
algal bloom5.4 Algae
allergic rhinitis19.1 Hypersensitivities
alternative pathway17.2 Chemical Defenses
alternative splicing11.3 RNA Transcription
amine group7.4 Proteins
amino groups7.4 Proteins
aminoacyl tRNA synthetase11.4 Protein Synthesis (Translation)
aminoglycoside resistance14.5 Drug Resistance, 14.5 Drug Resistance
amphipathic7.3 Lipids
Analytical epidemiology16.2 Tracking Infectious Diseases
anaphylactic shock19.1 Hypersensitivities
anti-AChR antibodies19.2 Autoimmune Disorders
Anti-nuclear antibodies (ANAs)19.2 Autoimmune Disorders
anti-Rh factor antibodies19.1 Hypersensitivities
antibody-dependent cell-mediated cytotoxicity (ADCC)18.1 Overview of Specific Adaptive Immunity, 19.1 Hypersensitivities
antifungal medications5.3 Fungi
antigen presenting cells (APCs)19.1 Hypersensitivities
antimicrobial peptides (AMPs)17.2 Chemical Defenses
antimicrobial susceptibility testing (AST)14.6 Testing the Effectiveness of Antimicrobials
antisense strand11.3 RNA Transcription
antivaxxers18.5 Vaccines
arachadonic acid19.1 Hypersensitivities
Archaeplastida5.4 Algae
Archaeplastids5.4 Algae
Artificial passive immunity18.5 Vaccines, 19.1 Hypersensitivities
ascocarps5.3 Fungi
Ascomycota5.3 Fungi
ascospores5.3 Fungi
Aspergillus flavus5.3 Fungi
atomic force microscope2.3 Instruments of Microscopy
atypical pneumonia4.4 Gram-Positive Bacteria
autocrine function17.2 Chemical Defenses
autoimmune hemolytic anemia20.3 Agglutination Assays
autoimmune polyendocrine syndromes (APS)19.2 Autoimmune Disorders
automated, cell-counting20.5 Fluorescent Antibody Techniques
avian influenza virus A16.3 Modes of Disease Transmission
Avocado sunblotch viroid6.4 Viroids, Virusoids, and Prions
B
B-cell maturation19.4 Immunodeficiency
Bacillariophyta5.4 Algae
bacterial toxins18.5 Vaccines
bacteriochlorophyll8.6 Photosynthesis
bacteriophage preparation6.1 Viruses
bacteriorhodopsin4.6 Archaea
Baltimore classification system6.1 Viruses
basidia5.3 Fungi
basidiocarps5.3 Fungi
Basidiomycota5.3 Fungi
basidiospores5.3 Fungi
Beijerinck6.1 Viruses
binary fission9.1 How Microbes Grow
binomial nomenclature1.2 A Systematic Approach
biological safety levels13.1 Controlling Microbial Growth
Biological transmission16.3 Modes of Disease Transmission
bioluminescence4.2 Proteobacteria
biopolymers7.4 Proteins
Blastomyces dermatitidis5.3 Fungi, 22.4 Respiratory Mycoses
blocking antibodies19.1 Hypersensitivities
blood-group antigens19.1 Hypersensitivities
blood-spinal cord barrier26.1 Anatomy of the Nervous System
bone marrow ablation19.4 Immunodeficiency
brightfield microscope2.3 Instruments of Microscopy
Broad Street cholera epidemic16.2 Tracking Infectious Diseases
bronchoalveolar lavage19.1 Hypersensitivities
brown algae5.4 Algae
Bruton X-linked agammaglobulinemia19.4 Immunodeficiency
budding yeasts5.3 Fungi
Burkholderia4.2 Proteobacteria
Burkholderia cepacia7.4 Proteins
Burkholderiales4.2 Proteobacteria
C
C-reactive protein (CRP)19.2 Autoimmune Disorders
calibration curve9.1 How Microbes Grow
Calvin-Benson cycle8.6 Photosynthesis
capsomere6.1 Viruses
carbapenem resistance14.5 Drug Resistance
carbapenemases14.5 Drug Resistance
carbohydrates7.3 Lipids
carbonyl group7.4 Proteins
carboxyl group7.4 Proteins
carboxylic acid7.4 Proteins
carrageenan5.4 Algae, 5.4 Algae
catabolite activator protein (CAP)11.7 Gene Regulation: Operon Theory
CCA amino acid binding end11.4 Protein Synthesis (Translation)
cell-mediated immune response19.4 Immunodeficiency
cellular respiration8.6 Photosynthesis
Center for Drug Evaluation and Research (CDER)12.4 Gene Therapy
Centers for Disease Control and Prevention16.1 The Language of Epidemiologists
Centers for Disease Control and Prevention (CDC)16.1 The Language of Epidemiologists
central nervous system (CNS)26.1 Anatomy of the Nervous System
cerebrospinal fluid (CSF)26.1 Anatomy of the Nervous System
Chamberland filters6.1 Viruses
Charophyta5.4 Algae
Cheese handler’s disease19.1 Hypersensitivities
chemical mediators17.2 Chemical Defenses
chemically defined medium9.6 Media Used for Bacterial Growth
Chlamydomonas5.4 Algae
Chlorella5.4 Algae
Chlorophyta5.4 Algae
Chromobacterium violaceum19.4 Immunodeficiency
chronic granulomatous disease19.4 Immunodeficiency
chronic infection6.2 The Viral Life Cycle
chronic inflammation17.5 Inflammation and Fever
chronic lymphocytic thyroiditis19.2 Autoimmune Disorders
chronic myelogenous leukemia19.4 Immunodeficiency
Chrysophyta5.4 Algae
chytrids5.3 Fungi
ciliated epithelial cells17.1 Physical Defenses
citrus tristeza virus6.2 The Viral Life Cycle
classical complement cascade19.1 Hypersensitivities
closed culture9.1 How Microbes Grow
Clostridium perfringens gastroenteritis24.3 Bacterial Infections of the Gastrointestinal Tract
cluster of differentiation (CD) molecules18.3 T Lymphocytes and Cellular Immunity
coarse focusing knob2.3 Instruments of Microscopy
Coccidioides immitis5.3 Fungi, 22.4 Respiratory Mycoses
coenocytic hyphae5.3 Fungi
colony-forming unit9.1 How Microbes Grow
commercial sterilization13.1 Controlling Microbial Growth
competitive inhibitor8.1 Energy, Matter, and Enzymes
complement activation17.2 Chemical Defenses
complementary base pairing10.2 Structure and Function of DNA
complementary base pairs10.2 Structure and Function of DNA
complementary strand11.2 DNA Replication
concentrated animal feeding operations (CAFOs)14.5 Drug Resistance
conditional mutation11.5 Mutations
confocal microscopy9.1 How Microbes Grow
conidia5.3 Fungi
conjugate vaccine18.5 Vaccines, 18.5 Vaccines
conjugated proteins7.4 Proteins
constitutive secretory pathways3.4 Unique Characteristics of Eukaryotic Cells
constitutively expressed11.7 Gene Regulation: Operon Theory
continuous common source spread16.2 Tracking Infectious Diseases
convalescent phase20.3 Agglutination Assays
Coulter counter9.1 How Microbes Grow
Crenarchaeota4.6 Archaea
Creutzfeldt-Jakob disease (CJD)1.3 Types of Microorganisms
cross-resistance14.5 Drug Resistance
crustose lichens5.5 Lichens
cucumber mosaic virus6.2 The Viral Life Cycle
culture density9.1 How Microbes Grow
culture medium9.1 How Microbes Grow
cutaneous mycoses21.4 Mycoses of the Skin
cyclic photophosphorylation8.6 Photosynthesis
cytochrome oxidase8.3 Cellular Respiration
Cytophaga-Flavobacterium-Bacteroides (CFB)4.1 Prokaryote Habitats, Relationships, and Microbiomes
cytotoxic hypersensitivities19.1 Hypersensitivities
cytotoxic T lymphocyte19.1 Hypersensitivities
D
darkfield microscope2.3 Instruments of Microscopy
decimal reduction time (DRT)13.1 Controlling Microbial Growth
Deinococcus radiodurans4.5 Deeply Branching Bacteria
delayed-type hypersensitivities (DTH)19.1 Hypersensitivities
Deltaproteobacteria4.2 Proteobacteria
denatured7.4 Proteins
deoxyribonucleic acid (DNA)10.2 Structure and Function of DNA
Descriptive epidemiology16.2 Tracking Infectious Diseases
Desulfovibrio4.2 Proteobacteria
diabetes mellitus19.4 Immunodeficiency
Dictyostelium discoideum5.1 Unicellular Eukaryotic Parasites
Differential interference contrast (DIC) microscopes2.3 Instruments of Microscopy
diglyceride7.3 Lipids
dikaryotic5.3 Fungi
dimorphic fungi5.3 Fungi
dipeptide7.4 Proteins
Diphylobothrium latum5.2 Parasitic Helminths
direct agglutination assay20.3 Agglutination Assays
direct antihuman globulin test (DAT)20.3 Agglutination Assays
direct contact transmission16.3 Modes of Disease Transmission
direct Coombs’ test20.3 Agglutination Assays
Direct fluorescent antibody (DFA) tests20.5 Fluorescent Antibody Techniques
direct hemagglutination assays20.3 Agglutination Assays
direct immunofluorescence assay (DFA)2.3 Instruments of Microscopy
direct microscopic cell count9.1 How Microbes Grow
direct repair11.5 Mutations
Dirofilaria immitis,5.2 Parasitic Helminths
disaccharide7.2 Carbohydrates
disulfide bridge7.4 Proteins
DNA replication11.5 Mutations
double-stranded origin (dso) site11.2 DNA Replication
Dracunculus medinensis5.2 Parasitic Helminths
drug resistance14.5 Drug Resistance
dry weight of a culture sample9.1 How Microbes Grow
E
Eastern equine encephalitis (EEE)26.3 Acellular Diseases of the Nervous System
Ebola virus18.5 Vaccines
Echinococcus granulosus5.2 Parasitic Helminths
Edward Jenner18.5 Vaccines
electrochemical gradient8.6 Photosynthesis
electromagnetic radiation (EMR)2.1 The Properties of Light
electron transport system8.6 Photosynthesis
electron transport system (ETS)8.3 Cellular Respiration
electronic cell counting device9.1 How Microbes Grow
elongation in DNA replication11.2 DNA Replication
elongation in transcription11.3 RNA Transcription
elongation of translation11.4 Protein Synthesis (Translation)
Embden-Meyerhof-Parnas (EMP) pathway8.2 Catabolism of Carbohydrates
Embden-Meyerhof-Parnas pathway8.4 Fermentation
emerging infectious diseases16.4 Global Public Health
endocrine function17.2 Chemical Defenses
endothelial cells17.1 Physical Defenses
Enterobacter4.2 Proteobacteria
Enterobacter spp.14.5 Drug Resistance
Enterococcus faecium14.5 Drug Resistance
Enterocystozoan bieneusi5.3 Fungi
enterohemorrhagic E. coli (O157:H7)15.2 How Pathogens Cause Disease
enterotoxigenic E. coli10.2 Structure and Function of DNA
Entner-Doudoroff (ED) pathway8.2 Catabolism of Carbohydrates
enveloped virus6.1 Viruses
enzyme-linked immunosorbent assays (ELISAs)20.4 EIAs and ELISAs
epiphytes5.5 Lichens
epithelial cells17.1 Physical Defenses
Epsilonproteobacteria4.2 Proteobacteria
ergosterols5.3 Fungi, 5.3 Fungi
erythrocyte antigen19.1 Hypersensitivities
ESKAPE pathogens14.5 Drug Resistance
ether linkages4.6 Archaea
Euryarchaeota4.6 Archaea
ex situ bioremediation8.7 Biogeochemical Cycles
Experimental epidemiology16.2 Tracking Infectious Diseases
exponential growth phase9.1 How Microbes Grow
extended-spectrum β-lactamases (ESBLs)14.5 Drug Resistance
extensively drug-resistant Mycobacterium tuberculosis14.5 Drug Resistance
extracellular pathogens19.4 Immunodeficiency
extracellular polymeric substances (EPS)9.1 How Microbes Grow
extremophiles4.6 Archaea
F
facultative intracellular pathogens15.2 How Pathogens Cause Disease
fatal familial insomnia6.4 Viroids, Virusoids, and Prions
fatty acid7.3 Lipids
fatty acid methyl ester (FAME) analysis7.5 Using Biochemistry to Identify Microorganisms
fecal transplantation17.1 Physical Defenses
flavin adenine dinucleotide8.1 Energy, Matter, and Enzymes
flesh-eating bacterial syndrome21.2 Bacterial Infections of the Skin and Eyes
fluorescence in situ hybridization (FISH)2.3 Instruments of Microscopy, 2.4 Staining Microscopic Specimens
fluorescence-activated cell sorter (FACS)20.5 Fluorescent Antibody Techniques
fluorescent antibody (FA) techniques20.5 Fluorescent Antibody Techniques
fluorescent enzyme immunoassays (FEIAs)20.4 EIAs and ELISAs
foliose lichens5.5 Lichens
Food and Drug Administration12.4 Gene Therapy
formed elements17.3 Cellular Defenses
frameshift mutation11.5 Mutations, 11.5 Mutations
fruiting bodies4.2 Proteobacteria
frustules5.4 Algae
fruticose lichens5.5 Lichens
functional groups7.1 Organic Molecules
fungicides5.3 Fungi
G
gastrointestinal tract19.4 Immunodeficiency
generation time9.1 How Microbes Grow
genetically modified organisms (GMOs)16.3 Modes of Disease Transmission
germ-line gene therapy12.4 Gene Therapy
Gerstmann-Straussler-Scheinker disease6.4 Viroids, Virusoids, and Prions
giant viral species6.1 Viruses
glycolipid7.3 Lipids
glycoprotein7.4 Proteins
glycosidic linkage7.2 Carbohydrates
golden algae5.4 Algae
Gonyaulax5.4 Algae
graft-versus-host disease (GVHD)19.3 Organ Transplantation and Rejection
granulomatous lesions22.4 Respiratory Mycoses
green algae5.4 Algae
Griffith’s transformation experiments10.1 Using Microbiology to Discover the Secrets of Life
Guillain-Barré syndrome (GBS)26.1 Anatomy of the Nervous System
Guinea worm disease5.2 Parasitic Helminths
H
H1N1 influenza6.1 Viruses
Halobacterium salinarum4.6 Archaea
Haloferax volcanii4.6 Archaea
Hashimoto thyroiditis19.2 Autoimmune Disorders
healthcare-associated infections (HAI)16.3 Modes of Disease Transmission
helical virus6.1 Viruses
helminth infections19.1 Hypersensitivities
hemagglutination inhibition (HAI) assays6.3 Isolation, Culture, and Identification of Viruses
hematopoietic stem cells (HSCs)17.3 Cellular Defenses
hemoglobin-binding protein (Hgp)26.2 Bacterial Diseases of the Nervous System
hemolytic disease of the newborn20.3 Agglutination Assays
hemolytic disease of the newborn (HDN)19.1 Hypersensitivities, 19.1 Hypersensitivities
hemolytic reaction19.1 Hypersensitivities
hemolytic transfusion reaction (HTR)19.1 Hypersensitivities, 19.1 Hypersensitivities
hemolytic transfusion reactions20.3 Agglutination Assays
hemovigilance systems19.1 Hypersensitivities
hepatitis A,18.5 Vaccines
hepatitis B virus (HBV)6.4 Viroids, Virusoids, and Prions
Hepatitis C virus6.2 The Viral Life Cycle
hepatitis delta virus (HDV)6.4 Viroids, Virusoids, and Prions
hereditary angioedema17.5 Inflammation and Fever
herpes simplex virus type 1 (HSV-1)24.2 Microbial Diseases of the Mouth and Oral Cavity
herpes simplex virus type 2 (HSV-2)23.4 Viral Infections of the Reproductive System
heterolactic fermentation8.4 Fermentation
hexose monophosphate shunt8.2 Catabolism of Carbohydrates
Hib polysaccharide conjugate vaccine26.2 Bacterial Diseases of the Nervous System
high-efficiency particulate air (HEPA) filter13.2 Using Physical Methods to Control Microorganisms
high-energy phosphate bond8.1 Energy, Matter, and Enzymes
high-pressure liquid chromatography (HPLC)7.5 Using Biochemistry to Identify Microorganisms
high-resolution computed tomography (HRCT)19.1 Hypersensitivities
high-temperature short-time (HTST) pasteurization13.2 Using Physical Methods to Control Microorganisms
Histoplasma capsulatum5.3 Fungi, 22.4 Respiratory Mycoses
homolactic fermentation8.4 Fermentation, 8.4 Fermentation
Hooke’s law of elasticity2.3 Instruments of Microscopy
hopanoids7.3 Lipids
horizontal direct contact transmission16.3 Modes of Disease Transmission
host range6.1 Viruses
human leukocyte antigens (HLAs)19.3 Organ Transplantation and Rejection
human Rho(D) immune globulin19.1 Hypersensitivities
hydrocarbon chain7.3 Lipids
hydrocarbonoclastic bacteria9.6 Media Used for Bacterial Growth
hydrogen bonds7.4 Proteins
hydrophilic7.3 Lipids
hydroxyl group7.3 Lipids
hygiene hypothesis19.1 Hypersensitivities
hyperpigmentation19.2 Autoimmune Disorders
hypersensitivity19.1 Hypersensitivities
hypersensitivity pneumonitis (HP)19.1 Hypersensitivities
hyphae5.3 Fungi
Hyphomicrobium4.2 Proteobacteria
hyposensitization19.1 Hypersensitivities
hypothesis of causation16.2 Tracking Infectious Diseases
I
icosahedral6.1 Viruses
image point (focus)2.1 The Properties of Light
immunochromatographic assays20.4 EIAs and ELISAs
Immunocytochemistry (ICC)20.4 EIAs and ELISAs
immunodeficiency19.4 Immunodeficiency
immunofiltration20.4 EIAs and ELISAs
immunofluorescent staining6.1 Viruses
immunohematology19.1 Hypersensitivities
Immunohistochemistry (IHC)20.4 EIAs and ELISAs
immunostaining20.4 EIAs and ELISAs
in situ bioremediation8.7 Biogeochemical Cycles
Inactivated vaccines18.5 Vaccines
indirect agglutination assay20.3 Agglutination Assays
indirect antiglobulin test (IAT)20.3 Agglutination Assays
Indirect contact transmission16.3 Modes of Disease Transmission
indirect Coombs’ test20.3 Agglutination Assays
indirect ELISA20.4 EIAs and ELISAs
Indirect fluorescent antibody (IFA) tests20.5 Fluorescent Antibody Techniques
indirect immunofluorescence assay (IFA)2.3 Instruments of Microscopy
induced mutation11.5 Mutations
informed consent12.4 Gene Therapy
initiation of protein synthesis11.4 Protein Synthesis (Translation)
initiation of replication11.2 DNA Replication
initiation of transcription11.3 RNA Transcription
initiation of translation11.4 Protein Synthesis (Translation)
inorganic compound7.1 Organic Molecules
inorganic phosphate [Pi]8.1 Energy, Matter, and Enzymes
Institute of Medicine12.4 Gene Therapy
intercalating agent11.5 Mutations
intermittent common source spread16.2 Tracking Infectious Diseases
International Classification of Diseases15.1 Characteristics of Infectious Disease
International Classification of Diseases (ICD)6.1 Viruses
International Committee on Taxonomy of Viruses (ICTV)6.1 Viruses
International Union of Microbiological Societies6.1 Viruses
intestinal fluke5.2 Parasitic Helminths
intrinsic growth rate9.1 How Microbes Grow
Investigational New Drug (IND) application12.4 Gene Therapy
iron-sulfur protein8.3 Cellular Respiration
irritable bowel syndrome19.2 Autoimmune Disorders
isohemagglutinin19.1 Hypersensitivities
isoprene7.3 Lipids
isoprene chains4.6 Archaea
isoprenoids7.3 Lipids
Ivanovski6.1 Viruses
K
karyogamy5.3 Fungi
Korarchaeota4.6 Archaea
L
lactic acid bacteria (LAB)8.4 Fermentation
lactic acid fermentation8.4 Fermentation
lagging strand11.2 DNA Replication
Laminaria5.4 Algae
last universal common ancestor (LUCA)4.5 Deeply Branching Bacteria
latent infection6.2 The Viral Life Cycle
lateral flow tests20.4 EIAs and ELISAs
latex fixation assay20.3 Agglutination Assays
leading strand11.2 DNA Replication
lectin activation pathway17.2 Chemical Defenses
lepromatous (multibacillary) Hansen’s disease26.2 Bacterial Diseases of the Nervous System
light-dependent reaction8.6 Photosynthesis
light-harvesting complex8.6 Photosynthesis
light-independent reaction8.6 Photosynthesis, 8.6 Photosynthesis
Linnaean taxonomy1.2 A Systematic Approach
lipid-bilayer7.3 Lipids
lipooligosaccharide (LOS) endotoxin26.2 Bacterial Diseases of the Nervous System
lipoprotein7.4 Proteins
liposome7.3 Lipids
Live attenuated vaccines18.5 Vaccines
logarithmic (log) growth phase9.1 How Microbes Grow
Louis Pasteur18.5 Vaccines
lymphatic filariasis17.5 Inflammation and Fever
lysogenic conversion6.2 The Viral Life Cycle
Lytic animal viruses6.2 The Viral Life Cycle
M
Magnetospirillum magnetotacticum3.3 Unique Characteristics of Prokaryotic Cells
major basic protein (MBP)17.3 Cellular Defenses
major histocompatibility complex markers19.3 Organ Transplantation and Rejection
Mantoux skin test19.1 Hypersensitivities
mature transcript11.3 RNA Transcription
maximum growth temperature9.4 Temperature and Microbial Growth
maximum permissive oxygen concentration9.2 Oxygen Requirements for Microbial Growth