Chapter 26

a. A decrease in vasopressin production leads to normal glucose levels, an increased loss of water in the urine resulting in polyuria, an increased thirst (polydipsia), and an increased hunger (polyphagia).

b. CRH stimulates the release of adrenocorticotropic hormone from the anterior pituitary gland, which stimulates the release of cortisol from the adrenal cortex, decreasing cortisol production and leading to a decrease in the body’s stress response.

a. $\frac{150\mathrm{m}\mathrm{c}\mathrm{g}}{3\mathrm{d}\mathrm{o}\mathrm{s}\mathrm{e}\mathrm{s}}=\frac{50\mathrm{m}\mathrm{c}\mathrm{g}}{1\mathrm{d}\mathrm{o}\mathrm{s}\mathrm{e}}$
$\frac{50\mathrm{m}\mathrm{c}\mathrm{g}}{x\mathrm{m}\mathrm{L}}$ (desired dose) $=\frac{100\mathrm{m}\mathrm{c}\mathrm{g}}{1\mathrm{m}\mathrm{L}}$ (supply on hand)

b. Hydrocortisone is a steroid drug that can cause hyperglycemia and increase blood pressure. Monitoring for these potential adverse effects is essential to ensure client safety.

d. Acromegaly is a disorder caused by excessive growth hormone secretion from the pituitary, which results in abnormal growth of bones and soft tissues.

a. Fludrocortisone is a mineralocorticoid that can cause hypokalemia and hypertension. Monitoring for these adverse effects is essential to ensure client safety.

a. $\frac{120\mathrm{m}\mathrm{g}}{x\mathrm{m}\mathrm{L}}$ (desired dose) $=\frac{125\mathrm{m}\mathrm{g}}{2\mathrm{m}\mathrm{L}}$ (supply on hand)

therefore, the nurse should administer 1.9 mL per dose.

b. Glucocorticoid medications require a tapering dose to allow the adrenal glands to resume their normal function.

d. Bromocriptine is contraindicated in clients with uncontrolled hypertension.

b. In hyperaldosteronism, the kidneys reabsorb too much sodium and excrete too much potassium, leading to an increased blood volume and blood pressure and decreased potassium levels.