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psychomotor restlessness; an intense sensation of uneasiness or inner restlessness that usually involves the lower extremities and results in a compulsion to move
neuronal protein that regulates synaptic vesicle coordination and subsequent neurotransmitter release
lack of sweating due to decreased sweat glands
impaired balance and coordination that can affect any part of the body and speech
decrease in size or waste away, especially as a result of cellular degeneration
when the body's immune system cannot tell the difference between its own cells and foreign cells, the immune components mistakenly attack healthy body cells
rapid, involuntary jerking or flinging of proximal muscle groups
slowness of movement or progressive hesitations
monoamine neurotransmitters released in response to physical or emotional stress (e.g., epinephrine, dopamine)
slow, involuntary, writhing movements
damage to the myelin sheath that results in slowing or stopping of nerve impulses, leading to neurological problems
double vision—seeing two of the same image
difficulty with formulating words to speak
abnormality or impairment of voluntary movement
difficulty swallowing
movement disorder where muscles contract involuntarily, causing repetitive or twisting movements
increase in the severity of a disease or its signs and symptoms
glycoprotein molecules produced by B lymphocytes (plasma cells) that act as a critical part of the immune response by specifically recognizing and binding to particular antigens and aiding in their destruction
Lhermitte sign
transient electric shock sensation down the spine and extremities caused by neck flexion; most notably caused by MS
localized loss of adipose tissue
type of white blood cell that plays an essential role in the immune response (B and T lymphocytes); made in the bone marrow and found in the blood and lymph tissue
large, specialized connective tissue cells that recognize, engulf, and destroy target cells
handwriting that is very small
myelin sheath
protective insulated covering surrounding nerve fibers in the brain, spinal cord, and optic nerves
neuroleptic malignant syndrome (NMS)
a potentially life-threatening condition characterized by symptoms of confusion or altered mental states, muscle rigidity, hyperthermia, arrhythmias, and autonomic instability
neuropathic pain
pain that originates within the CNS or PNS resulting from damage or disease
involuntary oscillating eye movements that are usually rapid, repetitive, and uncontrolled
type of non-neuronal cells in the CNS that do not produce electrical impulses; main functions are to provide support and insulation to axons in the CNS
Parkinson’s disease (PD)
a progressive neurologic condition that destroys the pigmented dopaminergic neurons of the substantia nigra
deposits of neuron fragments surrounding a core of fibrillary amyloid beta-protein
progressive multifocal leukoencephalopathy (PML)
opportunistic, life-threatening viral infection of the brain caused by the John Cunningham virus
multiplying or increasing in number
decrease in or disappearance of signs and symptoms
continuous involuntary sustained muscle contraction that when passively stretched, the degree of resistance remains constant
tardive dyskinesia
movement disorder characterized by uncontrollable, abnormal, and repetitive movements of the face, torso, and/or other body parts

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