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acquired genetic factor
change that develops from exposure to risk factors
apoptosis
cell death
brachytherapy
type of radiation treatment in which a radioactive source is placed in or near a tumor; it can be a wire, seed, disc, capsule, or implant
cancer
disease caused by uncontrolled division of abnormal cells
carcinogen
substance or agent that can cause cancer
carcinoma
cancer that creates solid tumors
carcinoma in situ
cancer confined to the layer of cells where it began and has not spread to surrounding tissues
chemoreceptor trigger zone
area of the brain that detects toxins in the blood and cerebrospinal fluid and sends signals to the vomiting center of the brain
chemotherapy
cancer treatment that uses drugs to kill cancer cells or stop them from growing and dividing
differentiation
how mature or immature cancer cells look and behave compared to normal cells
external beam radiation
noninvasive method using high-energy radiation beams to destroy cancer cells
grading
process used to classify cancer cells based on how abnormal they appear when examined under a microscope
hyperviscosity syndrome
oncologic emergency in which the blood is so thick it will not flow properly
immunosurveillance
body’s monitoring process by which cells of the immune system detect and destroy premalignant of malignant cells
immunotherapy
type of cancer treatment that uses the body's immune system to fight cancer; involves stimulating the immune system to attack cancer cells or using antibodies to target specific cancer cells
innate genetic factor
mutation that is inherited
late effect
health problem that occurs months of years after treatment of cancer was completed
leukemia
cancer of the blood-forming tissues
lymphoma
cancer that begins in the lymphatic system
mucositis
inflammation and ulceration of the mucous membranes lining the digestive tract; common side effect of chemotherapy and radiation therapy
neuropathy
condition characterized by damage to the nerves, often causing pain, numbness, tingling, or weakness
neutropenia
condition in which there is a low count of immature white blood cells called neutrophils
oncological emergency
serious and often life-threatening complication of cancer or its treatment that requires immediate medical attention
radiation therapy (also, radiotherapy)
cancer treatment that uses radiation to kill cancer cells or shrink tumors
recurrence
new occurrence of something (cancer diagnosis) that has occurred, happened, or appeared in the past
remission
period when an illness is less severe, or manifestations of the illness are not actively affecting the person
sarcoma
malignancy of connective or nonepithelial tissue
staging
system used to describe the extent and spread of cancer in the body
stomatitis
inflammation and ulceration of the mouth and lips; common side effect of chemotherapy and radiation therapy
survivorship
state of surviving something that might have resulted in death; it applies to an individual from the time a cancer diagnosis is made throughout the remainder of their life
TNM system
method used for staging to describe the extent and spread of cancer based on the size of the tumor, whether or not the cancer has spread to nearby lymph nodes, and whether or not there is metastasis to distant organs or tissues
tumor suppressor gene
type of gene that normally inhibits cell growth and division, helping to prevent the development of cancer
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