Which of the following is a barrier against pathogens provided by the skin?
- high pH
 - mucus
 - tears
 - desiccation
 
Although interferons have several effects, they are particularly useful against infections with which type of pathogen?
- bacteria
 - viruses
 - fungi
 - helminths
 
Which organelle do phagocytes use to digest engulfed particles?
- lysosome
 - nucleus
 - endoplasmic reticulum
 - mitochondria
 
Which innate immune system component uses MHC I molecules directly in its defense strategy?
- macrophages
 - neutrophils
 - NK cells
 - interferon
 
Which of the following is both a phagocyte and an antigen-presenting cell?
- NK cell
 - eosinophil
 - neutrophil
 - macrophage
 
Which immune cells bind MHC molecules on APCs via CD8 coreceptors on their cell surfaces?
- TH cells
 - CTLs
 - mast cells
 - basophils
 
What “self” pattern is identified by NK cells?
- altered self
 - missing self
 - normal self
 - non-self
 
The acquired ability to prevent an unnecessary or destructive immune reaction to a harmless foreign particle, such as a food protein, is called ________.
- the TH2 response
 - allergy
 - immune tolerance
 - autoimmunity
 
A memory B cell can differentiate upon re-exposure to a pathogen of which cell type?
- CTL
 - naïve B cell
 - memory T cell
 - plasma cell
 
Foreign particles circulating in the blood are filtered by the ________.
- spleen
 - lymph nodes
 - MALT
 - lymph
 
The structure of an antibody is similar to the extracellular component of which receptor?
- MHC I
 - MHC II
 - BCR
 - none of the above
 
The first antibody class to appear in the serum in response to a newly encountered pathogen is ________.
- IgM
 - IgA
 - IgG
 - IgE
 
What is the most abundant antibody class detected in the serum upon reexposure to a pathogen or in reaction to a vaccine?
- IgM
 - IgA
 - IgG
 - IgE
 
Breastfed infants typically are resistant to disease because of ________.
- active immunity
 - passive immunity
 - immune tolerance
 - immune memory
 
Allergy to pollen is classified as:
- an autoimmune reaction
 - immunodeficiency
 - delayed hypersensitivity
 - immediate hypersensitivity
 
A potential cause of acquired autoimmunity is ________.
- tissue hypersensitivity
 - molecular mimicry
 - histamine release
 - radiation exposure
 
Autoantibodies are probably involved in:
- reactions to poison ivy
 - pollen allergies
 - systemic lupus erythematosus
 - HIV/AIDS
 
Which of the following diseases is not due to autoimmunity?
- rheumatic fever
 - systemic lupus erythematosus
 - diabetes mellitus
 - HIV/AIDS