1
.
A diploid cell has how many times the number of chromosomes as a haploid cell?
-
four times
-
half
-
one-fourth
-
twice
2
.
The first level of DNA organization in a eukaryotic cell is maintained by which protein?
-
cohesion
-
condensin
-
chromatin
-
histone
3
.
What inherited feature, in specific combinations, determines an organism’s traits?
-
cell membranes
-
genes
-
proteins
-
RNA
4
.
What are identical copies of chromatin held together by cohesin at the centromere called?
-
histones
-
nucleosomes
-
chromatin
-
sister chromatids
5
.
Chromosomes are duplicated during what stage of the cell cycle?
-
phase
-
prophase
-
pro-metaphase
-
S-phase
6
.
Which of the following events does not occur during some stage of interphase?
-
DNA duplication
-
increase in cell size
-
organelle duplication
-
separation of sister chromatids
7
.
Attachment of the mitotic spindle fibers to the kinetochores is a characteristic of which stage of mitosis?
-
anaphase
-
prophase
-
prometaphase
-
metaphase
8
.
The fusing of Golgi vesicles at the metaphase plate of dividing plant cells forms what structure?
-
actin ring
-
cell plate
-
cleavage furrow
-
mitotic spindle
9
.
What would be the outcome of blocking the S phase of interphase?
-
The cell would enter karyokinesis.
-
DNA replication would not occur.
-
Centrosomes would be duplicated.
-
The cytoskeleton would be dismantled.
10
.
At which of the cell cycle checkpoints do external forces have the greatest influence?
-
checkpoint
-
checkpoint
-
M checkpoint
-
checkpoint
11
.
If the M checkpoint is not cleared, what stage of mitosis will be blocked?
-
prophase
-
prometaphase
-
metaphase
-
anaphase
12
.
Which protein is a positive regulator that phosphorylates other proteins when activated?
-
p53
-
retinoblastoma protein (Rb)
-
cyclin
-
cyclin-dependent kinase (Cdk)
13
.
Which negative regulatory molecule can trigger apoptosis if vital cell cycle events do not occur?
-
p53
-
p21
-
retinoblastoma protein (Rb)
-
cyclin-dependent kinase (Cdk)
14
.
What is the main prerequisite for clearance at the checkpoint?
-
The cell has a reached a sufficient size.
-
The cell has an adequate stockpile of nucleotides.
-
An accurate and complete DNA replication has occurred.
-
Proper attachment of mitotic spindle fibers to kinetochores has occurred.
15
.
What do you call changes to the order of nucleotides in a segment of DNA that codes for a protein?
-
proto-oncogenes
-
tumor suppressor genes
-
gene mutations
-
negative regulators
16
.
Human papillomavirus can cause cervical cancer. The virus encodes E6, a protein that binds p53. Based on this fact and what you know about p53, what effect do you think E6 binding has on p53 activity?
-
E6 activates p53.
-
E6 protects p53 from degradation.
-
E6 mutates p53.
-
E6 binding marks p53 for degradation.
17
.
What is a gene that codes for a positive cell cycle regulator called?
-
kinase inhibitor
-
oncogene
-
proto-oncogene
-
tumor suppressor gene
18
.
Which molecule is a Cdk inhibitor or is controlled by p53?
-
anti-kinase
-
cyclin
-
p21
-
Rb
19
.
Which eukaryotic cell cycle events are missing in binary fission?
-
cell growth
-
DNA duplication
-
karyokinesis
-
cytokinesis
20
.
Which of the following statements about binary fission is false?
-
In both prokaryotic and eukaryotic cells, the outcome of cell reproduction is a pair of daughter cells, which are genetically identical to the parent cell.
-
Karyokinesis is unnecessary in prokaryotes because there is no nucleus.
-
Replication of the prokaryotic chromosome begins at the origin of replication and continues in both directions at once.
-
The mitotic spindle draws the duplicated chromosomes to the opposite ends of the cell followed by formation of a septum and two daughter cells.
21
.
The formation of what structure, which will eventually form the new cell walls of the daughter cells, is directed by FtsZ?
-
contractile ring
-
cell plate
-
cytoskeleton
-
septum